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HaPILLness
For Animal Welfare

The present invention provides an innovative technological solution to leverage the 3Rs principles towards a more humane alternative of rodents’ precise oral drug dosing.
  • Oral administration of drugs and bioactive compounds to rodents.
  • Production of toxicant baits for rodents.

Preserve metabolic profile and welfare
HIGHT ACCEPTANCE INDEX

Allows for individual precise dosing

Requires small amounts of drug

(when compared to drugs admixed in the food or drinking water)

Overcomes drug hydrophilicity/lipophilicity requirements for vehicle-solubilization.

Does not elicit significant stress responses.

Is efficient for repetitive and long-term delivery of bioactive compounds into rodents.

Preserve metabolic profile and welfare of experimental laboratory rodents.

2021
REFINEMENT PRIZE

The European Partnership for Alternative Approaches to Animal Testing (EPAA) gives the award to Ines Mendes Preguiça for the HaPILLness case study.

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